I used to really like large caliber handguns but in recent years the 460 has become just a little too much for me to handle ( bad wrist). There's obviously little need for a 460 or 500 unless you find yourself in very remote places where large dangerous game are the norm. The 460 is a handful at 2330 FPS/ 200 grain... visible muzzle blast in sunlight lol, pretty rough kick even with the 8.38" barrel length & 72 oz weight, and it's a lot to carry at an overall length of 15". It's a loud gun too! I'm only able to shoot it with 2 levels of hearing protection... plugs plus muffs. 460 & 454 Casull rounds are insanely expensive as well, unless you're going to shoot 45 Colt which makes the gun feel completely lame. I've never shot a 500 but some of those factors may be worth considering if wanting to get into a 500. I had my eye on a DE 50 cal for a few years but after the 460, I'm glad I didn't get it. I still love shooting my 44 mag but that's about as much caliber as I'll ever want in a handgun. Love the 629 btw!